This is quite interesting. The team at Realm Pictures has created an interactive Hitman experience in which people control a real Agent 47 (well, real in the sense that he's played by a bald, barcoded actor) as they look for targets in a sprawling, item-filled mansion. As in the game, the participants who are sitted in a room where they can access to maps, contact the NPCs and more, take control of the Agent 47 character, telling him where to go and what to do. Also like the game, it doesn't always work out for Agent 47, if you mess up, he gets "shot" and you start over.
Take a look at the video above to see how it works; the production values are pretty great.
Obviously, this is not very practical, as Agent 47 being followed around by a camera operator is not the best for stealth.